姜长涛
Changtao Jiang

北京大学教授
基础医学院副院长
免疫学系主任
国家杰出青年科学基金获得者
科学探索奖获得者

Ph.D., Professor
Peking University

姜长涛，北京大学教授，基础医学院副院长，免疫学系主任，国家杰出青年科学基金获得者、科学探索奖获得者。从事肠道菌群及其菌源酶与代谢性疾病的研究。提出“肠道菌源酶跨物种调控宿主稳态”新理论：提出菌源宿主同工酶的新概念，揭示菌源宿主同工酶DPP4介导临床降糖药物响应性的分子机制，并开发首个菌源DPP4的抑制剂；发现菌群—宿主互作的关键信使—胆汁酸的全新菌源修饰类型及生物合成通路，是脂肪性肝炎防治的新策略；发现降解尼古丁的肠道共生菌及其在脂肪性肝炎发病中的关键保护作用。以通讯作者在Cell (2024)、Science (2023)、Nature (2022)等期刊发表论文20余篇，其中6篇入选高被引论文，1篇获F1000最高等级推荐，11篇得到国际知名学者推荐及同期评述，受邀在Nature Reviews Endocrinology、Cell Host & Microbe等期刊发表综述或述评10篇，入选Cell Metabolism杂志编委。获授权发明专利7项，成立“北大医学—蒙牛集团营养与代谢健康联合实验室”。获中国生命科学十大进展、北京市自然科学一等奖（第一完成人）、科学探索奖、中国青年科技奖、谈家桢生命科学创新奖等奖励。主持基金委重大研究计划集成项目、重点项目、专项项目、国家重点研发计划等十余项基金。

Changtao Jiang, Ph.D., is a tenured full professor at Peking University, serving as the chair of Department of Immunology and the deputy dean of the School of Basic Medical Sciences. He is the recipient of The National Science Fund for Distinguished Young Scholars and XPLORER PRIZE. His work aims at gut microbiota, their microbial enzymes and their impact on metabolic diseases. In short, he pioneers a new theory of "cross-kingdom regulation of host homeostasis by gut microbial enzymes". The research results include the following: proposing a new concept of “microbial-host isozymes”; revealing a novel bile acid modification type and elucidating the role of microbial bile acid converting enzymes in non-alcoholic steatohepatitis (NASH); uncovering a nicotine-degrading gut bacterium and its protective role in NASH. He has published more than 20 SCI papers in Cell (2024), Science (2023), Nature (2022), and other journals, among which, 6 papers are highly cited papers, one paper is picked up by F1000Research and 11 papers are highlighted and by internationally recognized scholars in the field. He is also invited to serve on the editorial board of Cell Metabolism. He has obtained 7 authorized national invention patents, and established the "Peking University Health Science-Mengniu Nutrition and Metabolic Health Joint Laboratory". He has obtained Top 10 Chinese life scientific advances, First prize of Beijing Science and Technology (the first finisher), XPLORER PRIZE, China Youth Science and Technology Award and C.C. Tan Life Science Awards. He is supported by Major Program of National Natural Science Foundation of China, and State Key Program of National Natural Science of China.